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| Synonym: | Peanut agglutinin, PNA |
Description
| Biochem/physiol Actions | PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase treated erythrocytes. PNA has potent anti-T activity similar to the anti-T antibody in human sera. The lectin can be used to distinguish between human lymphocyte subsets. |
| Physical form | Suspension in 1.0 M NaCl containing 0.01% thimerosal |
Properties
| form | saline suspension |
| extent of labeling | 2-4 mg per mL |
| matrix | 6% agarose macrobeads |
| matrix activation | cyanogen bromide |
| matrix attachment | amino |
| matrix spacer | 1 atom |
| capacity | ~0.5 mg/mL binding capacity (asialofetuin (A 4781)) |
| conjugate | agarose conjugate |
| storage temp. | 2-8°C |
References
| reference | Lotan, R. J. Biol. Chem. 250, 8518, (1975) |
| | London, J. J. Immunol. 121, 438, (1978) |
| | Bird, G. W. G. Vox Sang. 9, 748, (1964) |